To the recipient, spam is easily recognizable. If you hired someone to read your mail and discard the spam, they would have little trouble doing it. How much do we have to do, short of AI, to automate this process?
I think we will be able to solve the problem with fairly simple algorithms. In fact, I've found that you can filter present-day spam acceptably well using nothing more than a Bayesian combination of the spam probabilities of individual words. Using a slightly tweaked (as described below) Bayesian filter, we now miss less than 5 per 1000 spams, with 0 false positives.
The statistical approach is not usually the first one people try when they write spam filters. Most hackers' first instinct is to try to write software that recognizes individual properties of spam. You look at spams and you think, the gall of these guys to try sending me mail that begins "Dear Friend" or has a subject line that's all uppercase and ends in eight exclamation points. I can filter out that stuff with about one line of code.